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Obesity medication targets the biologic systems that regulate appetite, satiety, energy balance, and nutrient handling

The stack signals the somatotroph cells in the anterior pituitary gland to release a pulse of human growth hormone (HGH)

GLP-1 receptor agonists work by mimicking the action of this hormone , which is released from the intestine in response to food intake

The stomach is a harsh environment

The TPP dataset is provided as a supplementary file

In addition to providing recommendations for achieving glycaemic control, current type 2 diabetes guidelines emphasise the importance of weight loss through lifestyle changes, surgical interventions or medications [6, 7]