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GD contributed to the final revision of the manuscript

Similarly, one other study found that valproic acid has neuroprotective and anti-apoptotic impacts against traumatic brain injury via increasing the expression of AKT and ERK, and that these signaling pathways facilitate VPA neuroprotection (Zhang et al., 2014)

Similarly, there is no evidence that multiple doses of activated charcoal do increase the elimination of VPA or toxic metabolites

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