Zhang Z, Jia J, Lai Y, Ma Y, Weng J, Sun L
1C), suggesting that the A39 4CA mutant is an active transporter, while another cysteine mutant of the substrate binding site A39 C334S -FLAG can only rescue partially (Fig
PMID 17067183
Impaired intestinal sugar transport in cirrhotic rats: correction by low doses of insulin-like growth factor I
The DDX3X degrader J10 shows enhanced cytotoxic activity relative to RK-33 In our pursuit of evaluating DDX3X as a therapeutic target in lung cancer, we conceived twelve potential heterobifunctional DDX3X degraders using Proteolysis Targeting Chimeras (PROTACs) technology [44], which leverage the ubiquitin-proteasome system to induce DDX3X degradation (Fig
Elkelish A, El-Mogy MM, Niedbaa G, Piekutowska M, Atia MA, Hamada MM, et al