medRxiv [Preprint] 2024 Feb 18 2
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DOI: Published online: April 25, 2016 Department of Internal Medicine, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea
The first AREDS demonstrated a reduction in the risk of progression to end-stage AMD when beta carotene (7,500 mcg RAE [15 mg]), vitamin C (500 mg), vitamin E (180 mg [400 IU]), zinc (80 mg), and copper (2 mg) were given daily to people with advanced forms of both wet and dry AMD
Injection-site reactions and tolerability: Creating a subcutaneous depot that lasts for weeks means the formulation (or its remnants) resides in tissue for a long time