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The SCFAs acetate (C2), propionate (C3), and butyrate (C4), produced by various microbial species in the gut are the most prevalent anions or metabolites in the gut which have a substantial role in psychiatric diseases (68, 69), in both direct and indirect ways (67)

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Recent studies have suggested that glycemic variability may serve as an independent risk factor for DN, affecting both peripheral and autonomic nerve functions (Zhang X