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Moreover, immunofluorescence assays showed that SP decreased the mean fluorescence intensity of KEAP1, whereas it increased the co-localization of KEAP1 and ubiquitin dose-dependently (Fig
While the number of subjects in this study for genomic analysis was small, the analysis of eight specimens per lung representing different degrees of emphysema from each individual allowed us to detect gene expression changes specifically associated with regional emphysema severity
In a physician-led practice, medication interactions are part of the standard screening process
Comparing the schistosomicidal activity against juvenile worms with that of PZQ reported in previous in vivo studies 61 , the inhibitors reported herein show superior schistosomicidal activity to PZQ at the worm developmental stage in mice
