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As specified in the SAP, the statistical analyses employed an MMRM analysis using the REML as estimation method and structured covariance matrix with compound symmetry

Initial results (based on the first 4,600 patients data) demonstrated that PrecisionLife can identify genetic biomarkers associated with strong and weak responders to GLP-1 RA drugs and quantitatively predict the level of efficacy based on their degree of response measured by BMI changes and HbA1c changes

"It's an exciting moment after decades of unsuccessful attempts to find effective treatments for people living with obesity." Concerns About Industry Funding and Access A large share of the studies included in the reviews were funded by the companies that manufacture the drugs

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Use in children Semaglutide (Wegovy) subcutaneous (under the skin) injection is FDA-approved for adolescents aged 12 years and older with obesity for weight loss and management