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Anti-obesity Drugs Market Segment Analysis By Mechanism of Action: Multi-Agonists Redefine Efficacy Ceiling The segment generated USD 13.1 billion in 2025, when GLP-1 monotherapies held 38.55% share

MAPK signaling (via p-ERK and p-p38) upregulates both FFAR and GLP-1R expression, while the farnesoid X receptor (FXR) acts as a brake on this system and thereby suppress FFAR2 expression and dampen SCFA-induced GLP-1 release when activated

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DksA2, a Zinc-Independent Structural Analog of the Transcription Factor DksA

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