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Consequently, treatment becomes ineffective, leading to persistent infections 1,2

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The Mouse Brain in Stereotaxic Coordinates, 2 nd Edition

We further show that for ordered, semi-conservative repair (model 2), the NHEJ core factor complex continues to have an important role in guiding repair of the 2nd strand break, even though 2nd strand break repair could in principle be mediated by, e.g., SSBR