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Both pathway and individual metabolite analysis revealed differential abundance of tryptophan pathway intermediates in PBH, including tryptophan itself and its downstream metabolites kynurenic acid, xanthurenate, and serotonin (Figure 4)

Infection with viruses, such as hepatitis C (HCV), hepatitis E, parvovirus, rubella, herpes simplex, EpsteinBarr, or human T lymphotropic virus type 1 (HLTV1), could be involved in the pathogenesis of AITDs (58)

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Chemotherapy can cause various unpleasant side effects

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