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A 2023 American Society of Anesthesiologists guidance document recommends this 1-week hold, with daily formulations held on the day of surgery [15]

These agents disrupt key mitochondrial functions through diverse mechanisms

More specialised tests such as active B12 (holotranscobalamin) or methylmalonic acid may be available through specialist referral, though availability varies across the UK

Current NICE guidance continues to position metformin as the initial treatment for most adults with type 2 diabetes, reserving GLP-1 agonists for specific situations rather than universal first-line use

But on the USMLE, youre far more likely to see a question asking which drug is used and why

Recommended by LinkedIn Safety Profile Both medications were generally well tolerated