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In addition to immune and microbiota regulation, butyrate also exerts auxiliary metabolic effects that may indirectly benefit SLE patients

Oncoimmunology 7:e1391972 Ellerby HM, Arap W, Ellerby LM, Kain R, Andrusiak R, Rio GD, Krajewski S, Lombardo CR, Rao R et al (1999) Anti-cancer activity of targeted pro-apoptotic peptides

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There is a theoretical concern that aggressive senolytic clearance could remove this anti-tumor senescence signal, potentially accelerating tumor growth in individuals with pre-malignant cells

doi: 10.1083/jcb.202001161 78 ChangCJensenLEHurleyJH

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