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10.1139/cjpp-2016-0447 72 NohJ.-R.KimY.-H.HwangJ

The peptide retains activity in human gastric juice for more than 24 hours, tolerates pH from 1 to 11, and resists multiple proteolytic enzymes, properties that derive from the high proline content (four of fifteen residues) and the absence of cleavage-prone motifs

A phase 2 trial of exenatide in treating AD showed that patients displayed reduced amyloid- 42 concentrations, the abnormal accumulations that are a primary driver of AD

Protein Exp

Vlahopoulos SA, Logotheti S, Mikas D, Giarika A, Gorgoulis V, Zoumpourlis V

The toxicity of free iron is related to its ability to rapidly generate the highly toxic hydroxyl free radical (HO ) via the Fenton reaction