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The complexity of neurosteroid-mediated effects, for instance gating of GABA A R (109, 135139) and subunit-specific modulation of glycine and NMDARs (140), suggest the likelihood of multiple binding sites that contribute to potentiating and inhibitory effects ( A Rs also appears to involve modulation of subunit-containing receptors which play a role in tonic inhibition (141145)

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Properly reconstituted and refrigerated tirzepatide remains stable for 28 days from the date of reconstitution

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