This has led to speculation that GLP-2 may act indirectly on bone cells in humans, with the presence of GLP-2R on the parathyroid gland suggesting a potential link between GLP-2, PTH secretion, and bone turnover
Weve seen an improvement of 40-160% across bone parameters in our pre-clinical small animal studies for our novel oral small molecule GLP-1RA
Several factors influence whether this combined approach might be suitable, including the type of hormone therapy, your baseline health, and how your body responds to each treatment
Because there are no clear guidelines around microdosing, patients should only try it with caution and under medical care
10.1016/j.bcp.2021.114817 141 ZhuH.CaiH.WangX.ChenT.ZhenC.ZhangZ.et al (2022)
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