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The most significant clinical data for retatrutide to date comes from a Phase 2 randomised controlled trial published in the New England Journal of Medicine in 2023 (Jastreboff et al., NEJM 2023)

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These results show that GLP-1 induced gastroparesis affects the whole digestive system, not just the stomach

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Expect Potential Early Headaches Headache during the first two to four weeks of semaglutide treatment or during dose escalation is common and does not necessarily predict long-term headache outcomes

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