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MDA, an important marker of lipid peroxidation, is positively correlated with a decrease in glomerular filtration rate, suggesting that as CKD progresses, oxidative stress worsens, and ferroptosis could be a central driver of kidney damage [12]

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Hypoglycemia risk is major, and effects on fluid balance, joint comfort, and other parameters become more pronounced

Therapeutic medications usually come with a laundry list of possible side effects and consequences that pharmaceutical companies and healthcare agencies are legally required to disclose

The review also discusses renal targets and focuses on CKD progression, including associated biochemical pathways