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Leonurine (4-guanidino-n-butyl syringate), a naturally occurring alkaloid, is an active extract obtained from the plant commonly known as Chinese Motherwort (Leonurus heterophyllus) 26

In a recent study, exogenous DPP4 or upregulation of DPP4 in synovial fibroblasts was found to reduce the release of proinflammatory cytokines such as IL-6, IL-3, and IL-1

Food and Drug Administration has also generally recognized ergothioneine as safe

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PlexusDx compounded semaglutide injections ($189/month) offer a cost-effective way to continue therapy long-term if your provider recommends it

But the evidence base for GLP-1RAs in #HS has been thin, and providers have been navigating patient questions with limited data to draw on