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Second, pharmacokinetic sub-studies embedded within clinical trials should confirm systemic exposure at the population level, enabling post hoc correlation of plasma curcumin concentrations with clinical response a design feature that would substantially improve the mechanistic interpretability of outcomes

Barbosa FC, Silva M, Silva H, Albuquerque D, Gomes AAR, Silva S, et al

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The introduction of semaglutide represents a meaningful advancement in the management of CKD in patients with T2D

Journal of Endocrinological Investigation