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The gut flora as a forgotten organ

The analysis revealed that isoquercitrin decreased Keap1 expression, thereby promoting Nrf2 nuclear translocation and upregulating the expression of Nrf2 and its downstream target GCLC

doi: 10.1161/CIRCRESAHA.119.315939 138 ZhangXHouLGuoZWangGXuJZhengZet al

Another major function of GSH is the formation of phytochelatins (PCs) that bind heavy metals for safe transport and sequestration in the vacuole (Sharma and Dietz 2006)