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The mean baseline HbA1c, body mass index, and duration of diabetes were 9.0%, 28.8 kg/m 2 , and 11.7 years, respectively

Real-world results lag trial results largely because people stop

Evidence snapshot: The SURPASS and SURMOUNT trial programscomprising placebo- and active-controlled trialsare the primary clinical evidence base, consistently showing multi-domain cardiometabolic benefits across hundreds to thousands of participants

Vitamin B12 status and rate of brain volume loss in community-dwelling elderly

Tirzepatide represents a dual-action medication that activates both glucagon-like peptide-1 (GLP-1) and glucose-dependent insulinotropic polypeptide (GIP) receptors, making it distinct from single-action GLP-1 therapies

CPT Pharmacometrics & Systems Pharmacology, 13 (3), 494503