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This increase in energy helps combat fatigue, making it easier to stay active and motivated to exercise, which, in turn, burns more calories

Available online: 140.Pradeep H., Yenisetti S.C., Rajini P.S., Muralidhara M

doi: 10.1016/0300-483X(91)90004-K

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Repeated opioid use increases H3 acetylation in the mesolimbic DA system, notably at H3K9, H3K14, H3K18, and H3K27