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It has been reported that leptin can increase OS by inducing monocyte proliferation, resulting in increased NADPH oxidase activity

En resumen, prdidas de peso a partir del 5% producen beneficios en muchas de las comorbilidades cardiometablicas asociadas al sobrepeso/obesidad como la DM2, la DLP, la HTA o la inflamacin, y sobre la calidad de vida18

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The chronic condition of CM is attributable to repeated migraine attacks, and 2.5 % of episodic migraine converts into CM each year [4, 5]