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Description

2.1 APPLICATIONS OF THE REDOX-BASED PROTEOMICS APPROACH IN MDMA-EXPOSED TISSUES The redox-based, Cys-targeted approach using biotin-NM, as we originally described [5154], exhibited a major advantage in detecting subtle increments in the amounts of oxidatively-modified proteins over the previously existing methods of using biotin-conjugated iodoacetamide (BIAM) [60], 4-iodobutyl-triphenylphosphonium [61], or isotope-coded affinity tag (ICAT) reagent [62], mainly because the levels of oxidized proteins detected with these reagents (e.g., BIAM, 4-iodobutyl-triphenylphosphonium, or ICAT) are inversely related to the increased levels of oxidative stress

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The analysis involving individuals with moderate AD revealed minimal advancements in disease progression following the administration of vitamin E

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Kim Hildreth Kim is a NBHWC-certified Health Coach with a BA in Psychology & Nutrition, and a MA in Educational Leadership

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Int J Clin Pract 2019;73:e13399

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