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The Academy Award winner, who was diagnosed with Type 2 diabetes in 2017, shed 100 pounds over seven years after changing her diet and committing to a regular fitness routine

Ileal interposition surgery improves glucose and lipid metabolism and delays diabetes onset in the UCD-T2DM rat

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More serious but less common side effects include: Pancreatitis: This is inflammation of the pancreas, which can cause severe stomach pain, nausea, and vomiting

But because it is not FDA-approved, any theoretical advantage can be outweighed by practical concerns about product quality and oversight