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Notably, pathological iron accumulation has been consistently observed in the hippocampus and cortical regions of AD patients

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Briefly, 300,000 to 400,000 HeLa or U2OS cells were transiently cotransfected with precomplexed RNPs consisting of 100 to 150 pmol of chemically modified sgRNA (Synthego), 33 to 50 pmol of 3 NLS Sp Cas9 protein (St