Adrenaline (via activation of -adrenoceptors, elevation of cAMP and mobilisation of intracellular [Ca 2+ ] i ) is a powerful glucagon secretagogue [22]
Therefore, this hormone could be a promising candidate for combination therapy with GLP-1 for better control of T2D
Jardiance Prescribing Information
Lamb CA, Kennedy NA, Raine T, Hendy PA, Smith PJ, Limdi JK, et al
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Conscious of the importance of all the above, we argue for the need of and inquisitive mechanistic and clinically applied research to inform stakeholders about the potential benefits and harms of GLP-1RAs