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After a meal, insulin secretion is stimulated quickly and considerably in order to maintain plasma glucose concentrations within a narrow physiological range (Figure 1 highlights the physiology of the incretin hormones after a meal and the mode of action of DPP-4 inhibitors ( Figure 1 DPP-4 inhibitors have become an increasingly firmly established class of oral antidiabetic agents for the treatment of type 2 diabetes

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[Abstract]2024 Nov 14;67(21):18865-18882

In ischemia/reperfusion injured rat intestine, an infusion of intravenous trimetazidine (3 mg/kg) lowered malondialdehyde and myeloperoxidase, which is a pro-oxidative enzyme that catalyzes the formation of ROS [177]