The intermediate metabolites of glutamine can enter the TCA cycle, thus ensuring the replenishment of the TCA cycle under the condition of glucose deficiency
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10.1016/j.ejphar.2022.175213 2 AhmadN.AhmadR.AlrasheedR
Notably, an increase in the permeability of these new blood vessels promotes infiltration of various inflammatory factors into the cartilage, which exacerbates cartilage degeneration and OA severity (3,4)
Hong L, Chen G, Cai Z et al (2022) Balancing microthrombosis and inflammation via injectable protein hydrogel for inflammatory bowel disease
The rate-limiting step in extracellular GSH catabolism is controlled by -glutamyltransferases (GGTs), which cleave the -glutamyl bond in GSH to release glutamate and dipeptide cysteinylglycine