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This response involves three primary pathways: PKR-like ER kinase (PERK), inositol-requiring enzyme 1 alpha (IRE1), and activating transcription factor 6 (ATF6), all of which are activated under conditions of ER stress [49]

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Glutamate production from ammonia via glutamate dehydrogenase 2 activity supports cancer cell proliferation under glutamine depletion

OxLDL loading significantly depleted cytosolic and mitochondrial anisotropy in a time-dependent manner (Fig 4D), suggesting that oxLDL loading increased GSR-mediated NADPH consumption in both compartments

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