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Data Availability Statement All data on tirzepatide are included within this paper and its supplementary information files.

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CPAP = Continuous Positive Airway Pressure

Aging Cell 13 , 540550 (2014)

In glial cells, KYNA has also been noted to increase the expression of nerve growth factor [126], an important regulator of immunology and angiogenesis that meta-analyses have reported to be decreased in depressed patients compared to healthy controls [127, 128]