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Noel, R

When the ability to overeat is taken away, youre left with a flood of feelings to cope with

There are also safety considerations

A post hoc subgroup analysis assessing changes in BMI standard-deviation scores between participants with one or more gastrointestinal adverse events and those with none revealed that the effect of liraglutide in reducing BMI standard-deviation scores was independent of gastrointestinal adverse events (P = 0.82) (245)

What the biology reviewed in this article makes clear is that this framing has always been inadequate

Impact on NAION A paper published in 2024 in JAMA Ophthalmology created shock waves in the ophthalmic community by showing that subcutaneous semaglutide was associated with a significantly higher risk of developing nonarteritic anterior ischemic optic neuropathy (NAION)