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10.1093/TOXSCI/KFR183 [DOI] [PMC free article] [PubMed] [Google Scholar] Wu KC, Cui JY, Klaassen CD (2012) Effect of graded Nrf2 activation on phase-I and -II drug metabolizing enzymes and transporters in mouse liver

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While the trial failed to demonstrate a significant slowing in disease progression with either dose, the findings suggested that a subgroup of patients with early ALS and moderate disease progression could potentially benefit from the higher dose

Sulforaphane supplementation decreased amyloid plaque burden and improved cognitive performance in PS1V97L transgenic mice