If the late data keeps tracking Phase 2, Health Canada and FDA approval looks plausible around 2027 or 2028
The majority is stored in skeletal muscle (~60%) and bone (~30%), with additional pools found in the liver (~5%), skin (~5%), pancreas, kidney and brain 22
The rate of weight loss is greatest in the first weeks of therapy for both drug and placebo subjects and tends to decrease in succeeding weeks
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You start low, stay there for a few weeks, and then increase gradually
He closely monitors each patients response to the medication, ensuring that the initial dose is well-tolerated and that any potential side effects, such as nausea or abdominal discomfort, are minimized