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Age-related factors : Many patients prescribed GLP-1 medications are middle-aged or older, demographics where benign prostatic hyperplasia (in men) and overactive bladder syndrome (in both sexes) become more prevalent

In clinical trials and other studies, those drugs outperform liraglutide, producing substantially more weight loss while causing fewer side effects

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That extended duration is why semaglutide works as a once-weekly injection rather than requiring daily doses