keenly noted this and found that deleting this protein (termed OIL1) eliminated the oleaginous phenotype (Bhutada et al., 2018)
This TCA cycle suppression results in a large decrease in ATP, which adversely affects all ATP-dependent proteins, including those involved in nutrient transport, mobilization, and uptake, leading to mouse death
Dyrehag C
doi:10.1016/j.arr.2015.12.007 Gltrk MT, nal ZN, smi O, imen MB, nal M
Thankfully, hormone replacement therapy such as BHRT can be used as a tool when we find our hormones in flux
Acknowledgements The author is indebted to some of the 6th Form students of University College School, Hampstead, London UK for asking a series of questions which provided the inspiration behind this paper