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GSH dysfunction not only impairs GPX4 activity but also mobilizes intracellular Fe 2 + , thereby accelerating lipid peroxidation and ferroptotic death 131,132

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SGLT1 in pancreatic cells regulates glucagon secretion in mice, possibly explaining the distinct effects of SGLT2 inhibitors on plasma glucagon levels

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Once-daily liraglutide and the once-weekly agents can be taken at any time of day, whereas twice-daily exenatide and once-daily lixisenatide must be taken within 1 hour before eating (713)

IV hydration is one of the fastest ways to combat heat-related fatigue, especially during the summer months in South Florida