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The intervention consisted of diet and exercise counseling and randomization to intravenous infusion of bimagrumab (10 mg/kg up to 1200 mg in 5% dextrose solution) or placebo (5% dextrose solution) treatment every 4 weeks for 48 weeks

GLP-1 supplements and probiotics: Some products even make claims that are misleading or not backed by any science

GIP has been shown to decrease food intake & increase energy expenditure therefore resulting in weight reductions & when combined with GLP-1 receptor agonism, may result in greater effects on markers of metabolic dysregulation such as body weight, glucose, & lipides

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NLRP3: NLR Family Pyrin Domain Containing 3