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Look out for these symptoms: Persistent feelings of sadness or hopelessness Loss of interest in activities once enjoyed Changes in appetite or sleep patterns Fatigue or loss of energy Difficulty concentrating or making decisions If you notice any of these signs, talk to your doctor right away

Resuscitation from experimental traumatic brain injury by agmatine therapy

Others acknowledge that individual variations in MMP expression, copper metabolism, and skin sensitivity can create unexpected reactions

74 Witschi et al

During the taper, close monitoring is essential

doi: 10.1016/j.celrep.2015.09.036 122 StoneTWWilliamsRO