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Numerous other trials have demonstrated positive cardiovascular outcomes with focus on HFpEF in the SUMMIT trial for tirzepatide and the STEP-HFpEF trial for semaglutide [50,51,52]

However, since the liver plays a crucial role in detoxification and overall health, improving liver function with Hepafresh Injection may indirectly benefit the skin, particularly in cases where skin issues are linked to liver dysfunction

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In the case of canagliflozin, randomized clinical trials have demonstrated that it improves hepatic insulin sensitivity, as well as insulin secretion and clearance in patients with T2DM

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