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doi: 10.3906/sag-2002-237

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The reductions in PCSK1 levels, as a result of CerS2 ablation, are due to impaired processing of the pro-PCSK1 protein which normally occurs as it transits from the endoplasmic reticulum (ER) to the Golgi

Other symptoms include a cottony feeling in the mouth, redness, and soreness that make eating uncomfortable