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The brain again plays a crucial role in regulating kidney function, ensuring optimal renal blood flow, glomerular filtration rate, acidbase balance, and electrolyte balance through the ANS and the endocrine system (Afsar et al., 2016a)

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(2016) demonstrated in mouse models of middle cerebral artery occlusion that large ischemic strokes induce gut dysbiosis characterized by reduced diversity and Bacteroidetes overgrowth, leading to intestinal barrier dysfunction

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