Glucagon receptors : increase energy use and fat burning, while also reducing appetite
To understand what that timeline can look like, it helps to look at liraglutide, a medication that came before tirzepatide and followed a similar path from diabetes treatment to weight loss therapy and eventual generic availability
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Gutterman JU, Mavligit G, McBride C, Frei E 3rd, Freireich EJ, Hersh EM
(2023) covered additional pharmacokinetic profiles
Understanding their mechanistic distinctions is important for designing research protocols