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Although theres ongoing study about this specific side effect, we do have some believable reasons

doi:10.36849/JDD.8605 INTRODUCTION Glucagon-like peptide-1 (GLP-1) agonists are used to treat type 2 diabetes mellitus (T2DM) and have recently gained approval and popularity for treating obesity and weight loss

Most patients experience improvement in symptoms after 48 weeks of continued treatment as physiological adaptation occurs

Systemic rather than localized gut focus: While injectables can still benefit GI health indirectly, they are not as targeted to the mucosal lining as oral forms

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