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Network pharmacology has predicted 96 potential molecular targets and relevant signaling pathways, with KEGG analysis highlighting Bcl-2, BAD, JNK, p38, and ERK1/2 as key nodes
Gastrointestinal Tolerability Profiles And Dose Escalation Protocols Managing physiological response profiles requires gradual dose titration strategies in experimental models
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The laboratory studies suggest severe iron poisoning as evidenced by the drop in bicarbonate and arterial pH (metabolic acidosis as iron becomes hydrated and poisons the mitochondria), the rise in aminotransferases, fall in albumin, rise in prothrombin time and INR, and rise in total and conjugated bilirubin (liver failure) 4