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Routes that Bypass First-Pass Metabolism: Sublingual (e.g., nitroglycerin) Intravenous (IV) Rectal (partial) Transdermal patches Clinical Significance: Important when dosing oral medications to achieve therapeutic effect
Sometimes bleeding still occurs after the bandage and dressing are kept in place for several hours
Morphological, molecular analysis of tissue sections and of retina total protein extracts Sample preparation Eyes were removed and the corneas were eliminated at limbus level
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this inhibition increases urinary bicarbonate loss, slightly elevates urine pH, and explains both a predisposition to calcium-phosphate nephrolithiasis and the rare idiosyncratic syndrome of acute myopia with secondary angle-closure glaucoma
Lee Y, Lee S, Chang S-C, Lee J
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