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A novel and potent imidazo[4,5-c] quinolone derivative (NVP-BEZ235), which has entered phase I/II clinical trials in patients with advanced solid tumors, has a potential role in cisplatin-sensitive cancers by dual targeting of the PI3-K (phosphatidylinositol 3-kinase) and mTOR (mammalian target of rapamycin) kinases for NPC treatment

The biological scissors cut glutathione into its constituent amino acidscysteine, glutamic acid, and glycinemaking it useless as a whole antioxidant

estimated total GSH (GSH + GSSG) in RBCs to be 23 % heritable [34]

The gut microbiome: a core regulator of metabolism

Duvan, C

In silico screening-based discovery of novel inhibitors of human cyclic GMP-AMP synthase: a cross- validation study of molecular docking and experimental testing