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HepaRG cells (8000 cells/25 L/well) or PHHs (Hu8163, 17,500 cells/25 L/well) were seeded in collagen I-coated 384-well white flat-bottom plates (Corning, catalog: 354665)

Emerging preclinical research has identified GLP-1 receptors in various immune cells and tissues, leading to scientific interest in potential anti-inflammatory properties

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A key part of this process is paracrine signaling , where cells release growth factors, cytokines, and chemokines