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has been supported by MIUR - Ministero dellIstruzione Ministero dellUniversit e della Ricerca (Ministry of Education, University and Research) under the national project FSE/FESR - PON Ricerca e Innovazione 2014-2020 (N AIM1887574, CUP: E18H19000350007)

10.1016/j.mayocp.2018.09.013 42 SpalingerM