The hydroalcoholic extract of Aegle marmelos fruit (a component of chlorogenic acid, tannic acid, ferulic acid, gallic acid, and quercetin) can increase the swimming time to exhaustion in mice by 47.5% through the reduction of metabolite accumulation (87)
Furthermore, methionine contributes to the synthesis of glutathione, a primary cellular antioxidant, and carnitine, which is indispensable for the transport of long-chain fatty acids into the mitochondria for -oxidation
Limitations and Future Research Directions Despite biologically plausible mechanisms, important limitations remain
Glutamine is needed to produce the neurotransmitter called glutamate
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